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當(dāng)前位置:首頁產(chǎn)品中心抗體/抗原流式抗體S0B5287Alexa Fluor? 647 Mouse Anti-Rat CD71 Antibody (S-R638)

Alexa Fluor? 647 Mouse Anti-Rat CD71 Antibody (S-R638)
產(chǎn)品簡介:

Alexa Fluor? 647 Mouse Anti-Rat CD71 Antibody (S-R638)

產(chǎn)品型號:S0B5287

更新時間:2025-10-09

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CD71, also known as transferrin receptor 1 (TfR1), is a type II transmembrane glycoprotein that exists as a disulfide-linked homodimer on the cell surface. It plays a crucial role in cellular iron uptake by binding to iron-bound transferrin and mediating its internalization through receptor-mediated endocytosis. CD71 is widely expressed on proliferating cells, including erythroid precursors, activated immune cells, and various cancer cells. It is also a preferred entry receptor for several viruses, such as arenaviruses and hepatitis C virus. In addition, CD71 has been identified as a marker for cell proliferation and activation, and its expression is often used in the diagnosis and prognosis of hematological diseases.

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