13774214275
13774214275
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產品型號：S0B5291
更新時間：2025-10-09
廠商性質：生產廠家
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服務熱線15855403091
相關文章
CD38, also known as cyclic ADP ribose hydrolase, is a multifunctional transmembrane glycoprotein expressed on various immune cells such as T lymphocytes, B cells, and plasma cells. It functions as both a receptor and an enzyme, playing a crucial role in cell adhesion, signal transduction, and the regulation of intracellular calcium levels. CD38 catalyzes the metabolism of nicotinamide adenine dinucleotide （NAD+）, generating molecules like cyclic ADP-ribose （cADPR） and ADP-ribose （ADPR）, which are involved in calcium signaling and immune responses. It is highly expressed on myeloma cells and is used as a therapeutic target for multiple myeloma and other hematological malignancies. Additionally, CD38 is implicated in various physiological processes, including inflammation, phagocytosis, and antigen presentation, making it a subject of interest in both immunology and oncology.
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