Rat Anti-Mouse CD106 Antibody (S-R733)

產(chǎn)品型號(hào)：S0B5249

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

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產(chǎn)品介紹

CD106, also known as vascular cell adhesion molecule-1 （VCAM-1）, is a member of the immunoglobulin superfamily of proteins and is predominantly expressed in endothelial cells. It is a cytokine-inducible cell surface protein capable of mediating adhesion to leukocytes expressing alpha 4 integrins. CD106 plays a crucial role in various physiological and pathological processes. In embryonic development, CD106-deficient mouse embryos are not viable, showing severe defects in placental and heart development. In immune regulation, CD106 is involved in T cell activation and leukocyte recruitment to inflammation sites. It is also critical for mesenchymal stem cells （MSCs）-mediated immunosuppression and the binding of hematopoietic progenitor cells.

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