13774214275
13774214275
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產品型號：S0B5225
更新時間：2025-10-08
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服務熱線15855403091
相關文章
CD193, also known as C-C motif chemokine receptor 3 （CCR3）, is a member of the G protein-coupled receptor （GPCR） family, characterized by its seven-transmembrane structure. It is a high-affinity receptor for various chemokines, including eotaxin-1 （CCL11）, eotaxin-2 （CCL24）, eotaxin-3 （CCL26）, MCP-3 （CCL7）, MCP-4 （CCL13）, and RANTES （CCL5）. CD193 is highly expressed on eosinophils, basophils, and airway epithelial cells, and is also detected in CD4+ T cells, mast cells, monocytes, platelets, and CD34+ hematopoietic progenitor cells. This receptor plays a crucial role in mediating the migration and activation of eosinophils and other inflammatory cells, contributing to allergic responses and inflammatory processes in conditions such as asthma and allergic rhinitis. Additionally, CD193 has been identified as a co-receptor for HIV-1 entry into cells.
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