13774214275
13774214275
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產品型號：S0B5112
更新時間：2025-10-08
廠商性質：生產廠家
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服務熱線15855403091
相關文章
CD134, also known as OX40 or tumor necrosis factor receptor superfamily member 4 （TNFRSF4）, is a type 1 transmembrane glycoprotein and a secondary co-stimulatory immune checkpoint molecule involved in long-term T cell immunity. It is transiently expressed on activated CD4+ and CD8+ T cells after T cell receptor （TCR） ligation. The interaction between CD134 and its ligand, OX40L, enhances T cell activation, proliferation, survival, and cytokine production. CD134 is crucial for maintaining an immune response beyond the initial activation phase and is being investigated as a target in cancer immunotherapy, autoimmune disease modulation, and vaccine development.
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