13774214275
13774214275
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產品型號：S0B1515
更新時間：2025-10-07
廠商性質：生產廠家
訪問量：52
服務熱線15855403091
相關文章
CD45 is a member of the protein tyrosine phosphatase （PTP） family. CD45 is a type I transmembrane protein that is present in various isoforms on all differentiated hematopoietic cells （except erythrocytes and plasma cells）. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes via its extracellular domain （a form of co-stimulation）, or by activating various Src family kinases required for the antigen receptor signaling via its cytoplasmic domain. CD45 also suppresses JAK kinases, and so functions as a negative regulator of cytokine receptor signaling.
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