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當前位置:首頁產品中心抗體/抗原病理/IHC抗體S0B2317CD20 Recombinant Rabbit mAb (SDT-038-205)

CD20 Recombinant Rabbit mAb (SDT-038-205)
產品簡介:

CD20 Recombinant Rabbit mAb (SDT-038-205)

產品型號:S0B2317

更新時間:2025-10-10

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B-lymphocyte antigen CD20 or CD20 is expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells. It is found on B-cell lymphomas, hairy cell leukemia, B-cell chronic lymphocytic leukemia, and melanoma cancer stem cells. Immunohistochemistry can be used to determine the presence of CD20 on cells in histological tissue sections. Because CD20 remains present on the cells of most B-cell neoplasms, and is absent on otherwise similar appearing T-cell neoplasms, it can be very useful in diagnosing conditions such as B-cell lymphomas and leukaemias.

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