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當前位置:首頁產品中心抗體/抗原病理/IHC抗體S0B2304S-RMab? PU.1 Recombinant Rabbit mAb (SDT-R236)

S-RMab? PU.1 Recombinant Rabbit mAb (SDT-R236)
產品簡介:

S-RMab? PU.1 Recombinant Rabbit mAb (SDT-R236)

產品型號:S0B2304

更新時間:2025-10-10

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Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene. The PU.1 transcription factor is essential for hematopoiesis and cell fate decisions. PU.1 can physically interact with a variety of regulatory factors like TFIID, GATA-2, GATA-1 and c-Jun. The protein-protein interactions between these factors can regulate PU.1-dependent cell fate decisions. PU.1 can modulate the expression of 3000 genes in hematopoietic cells including cytokines. It is expressed in monocytes, granulocytes, B and NK cells but is absent in T cells, reticulocytes and megakaryocytes. Its transcription is regulated by various mechanisms.

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