13774214275
13774214275
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產品型號：S0B2240
更新時間：2025-10-10
廠商性質：生產廠家
訪問量：55
服務熱線15855403091
相關文章
Mucin 4 （MUC4）?is a highly glycosylated type I transmembrane glycoprotein. Normally acts as barrier to apical surface of epithelial cells, playing a protective and regulatory role. MUC4 expression is erroneous in many carcinomas and sarcomas, including sclerosing epithelioid fibrosarcoma?and pancreatic adenocarcinoma. Immunohistochemical staining for MUC4 has been discussed as a potential biomarker for detection of these cancers.?MUC4 can serve as a ligand for the oncogenic receptor ErbB2 and a modulator of its phosphorylation and signaling. MUC4 is frequently aberrantly expressed in epithelial tumors and can promote tumor growth and metastasis.
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