13774214275
13774214275
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產品型號：S0B2166
更新時間：2025-10-09
廠商性質：生產廠家
訪問量：65
服務熱線15855403091
相關文章
Fibroblast activation protein （FAP） is best known for its heightened expression in tumour stroma. This atypical serine protease has both dipeptidyl peptidase and endopeptidase activities, cleaving substrates at a post-proline bond. FAP expression is difficult to detect in non-diseased adult organs, but is greatly upregulated in sites of tissue remodelling, which include liver fibrosis, lung fibrosis, atherosclerosis, arthritis, tumours and embryonic tissues. Due to its restricted expression pattern and dual enzymatic activities, FAP is emerging as a unique therapeutic target [PMID: 24470260].
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