13774214275
13774214275
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產品型號：S0B2105
更新時間：2025-10-09
廠商性質：生產廠家
訪問量：71
服務熱線15855403091
PTEN is a dual-specificity phosphatase at two levels. First, PTEN has been shown to dephosphorylate protein substrates on serine/threonine and tyrosine residues, thus acting as a dual-specificity protein phosphatase. One example is the tyrosine dephosphorylation of focal adhesion kinase （FAK） to inhibit cell spreading. Second, PTEN also dephosphorylates phosphatidylinositol 3,4,5-trisphosphate （PIP3） to phosphatidylinositol 4,5-bisphosphate （PIP2） — hence, PTEN is also a dual-specificity phosphatase in the sense that it dephosphorylates lipid substrates in addition to protein substrates.
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