13774214275
13774214275
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產品型號：S0B0022
更新時間：2025-10-09
廠商性質：生產廠家
訪問量：82
服務熱線15855403091
相關文章
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. It is responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links （ICL）. It participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. ERCC1 is also required for homology-directed repair （HDR） of DNA double-strand breaks, in conjunction with SLX4.
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