13774214275
13774214275
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產品型號：S0B2046
更新時間：2025-10-09
廠商性質：生產廠家
訪問量：72
服務熱線15855403091
The p75 neurotrophin receptor （p75NTR） was first identified in 1973 as the low-affinity nerve growth factor receptor （LNGFR） before discovery that p75NTR bound other neurotrophins equally well as nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.
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