Mouse Anti-Human CD152 Antibody (S-R577)

產(chǎn)品型號(hào)：S0B5439

更新時(shí)間：2025-10-09

廠商性質(zhì)：生產(chǎn)廠家

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產(chǎn)品介紹

CD152, also known as CTLA-4 （cytotoxic T-lymphocyte-associated protein 4）, is a protein receptor that functions as an immune checkpoint. It is a member of the immunoglobulin superfamily and is expressed on the surface of T cells. The CD152 gene consists of 4 exons and encodes a protein with a signal peptide, an Ig-like domain, a transmembrane region, and a cytoplasmic domain. CD152 plays an essential role in regulating T cell activation by binding to its ligands CD80 and CD86, which are expressed on antigen-presenting cells. This binding can inhibit the over-activation of T cells, thus maintaining immune homeostasis.

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