FITC Mouse Anti-Rat CD86 Antibody (S-R580)

產(chǎn)品型號：S0B5202

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：44

服務(wù)熱線

15855403091

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

查看全部產(chǎn)品

相關(guān)文章

uPAR/CD87：腫瘤微環(huán)境中的“多面手”

從實驗室到臨床：蛋白激酶藥物的輝煌20年

功能性抗體：如何解鎖其在生物醫(yī)學(xué)研究中的無限潛能？

致癌分子的失控狂飆：EGFR 信號通路如何驅(qū)動腫瘤生長？

產(chǎn)品介紹

CD86, also known as B7-2, is a 70 kDa glycoprotein and a type I membrane protein that belongs to the immunoglobulin superfamily. It is primarily expressed on antigen-presenting cells （APCs） such as dendritic cells, macrophages, and B cells. CD86 serves as a ligand for two T cell surface proteins: CD28 and CTLA-4. The interaction between CD86 and CD28 provides a crucial co-stimulatory signal for T cell activation and survival, while binding to CTLA-4 negatively regulates T cell activation, thereby dampening the immune response. Additionally, CD86 plays a role in B cell function regulation and can influence IgG1 production. It is rapidly upregulated on B cells upon activation and can be induced on monocytes by interferon-gamma. CD86 is also involved in various immune processes, including the activation of the NF-kappa-B signaling pathway and the regulation of cytokine production.

上一個：S0B5203FITC Rabbit Anti-Human CD40 Antibody (S-145-45)