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產品型號:S0B5124
更新時間:2025-10-08
廠商性質:生產廠家
訪問量:46
服務熱線15855403091
CD1d is a non-polymorphic, MHC class I-like molecule that forms a heterodimer with β2-microglobulin and plays a crucial role in the immune system by presenting lipid antigens to invariant Natural Killer T (iNKT) cells. These lipid antigens can be derived from both self and non-self sources, including bacterial glycolipids and tumor-derived lipids. CD1d is expressed on various cell types, including myeloid and lymphoid cells, as well as epithelial and vascular smooth muscle cells. It is involved in regulating both innate and adaptive immune responses and has been implicated in antimicrobial, antitumor, and autoimmune activities. Additionally, CD1d is associated with diseases such as pulmonary tuberculosis and certain cancers.