Mouse Anti-Rat MHC II (RT1D) Antibody (S-R649)

產(chǎn)品型號(hào)：S0B5125

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

MHC II （Major Histocompatibility Complex Class II） proteins are a class of cell surface molecules expressed by antigen-presenting cells （such as dendritic cells, macrophages, and B cells）. They are responsible for presenting exogenous antigenic peptides to CD4+ T helper cells, thereby initiating adaptive immune responses. MHC II molecules consist of two transmembrane chains （α and β） that form a peptide-binding groove, which binds and displays antigenic peptides derived from extracellular pathogens or proteins. Their expression is regulated by immune modulators （such as IFN-γ） and plays a critical role in autoimmune diseases, transplant rejection, and infection immunity. The diversity of MHC II is encoded by highly polymorphic genes, ensuring a broad capacity for antigen recognition, making it a core mechanism of the immune system for identifying and eliminating pathogens.

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