Rat Anti-Mouse CD198 Antibody (S-R626)

產(chǎn)品型號(hào)：S0B5105

更新時(shí)間：2025-10-08

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

CD198, also known as C-C chemokine receptor type 8 （CCR8）, is a 41 kD G protein-coupled receptor with seven transmembrane regions, belonging to the beta chemokine receptor family. It is expressed by various immune cells, including subsets of thymocytes, Tregs, NKT cells, Th2-polarized cells, macrophages, monocytes, and monocyte-derived dendritic cells. CCR8 plays a role in mediating chemotaxis toward its ligands, such as CCL1 and CCL18, and is involved in the regulation of monocyte chemotaxis and thymic cell apoptosis. Additionally, CCR8 is associated with Th2 lymphocytes and has a role in allergic diseases. It is also considered an alternative coreceptor to CD4 for HIV-1 infection.

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